“We need to understand the ‘healthy’ brain before we can take the next step and distinguish differences in people suffering from neurological or psychiatric disorders,” explains Katrin Amunts. Leipzig, published by Johann Ambrosius Barth.Īlthough Brodmann’s discovery was groundbreaking, the hundredyear- old map is merely a schematic drawing, not the three-dimensional record that is needed today as a basis for comparison in modern imaging studies to assign patient data to the microscopic structures of the brain. Vergleichende Lokalisationslehre der Großhirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Lateral view of the brain map published by Korbinian Brodmann in 1909.Ĭopyright: Brodmann, K. Leipzig, Verlag von Johann Ambrosius Barth. Seitliche Ansicht der 1909 von Korbinian Brodmann veröffentlichten Gehirnkarte. Brodmann was convinced that each brain area is responsible for a specific function, an assumption that could only be proven for a small fraction of the areas with the resources available at that time,”. He not only created a cytoarchitectonic map, but also provided the basis for later comparative neuroanatomical investigations. “The psychiatrist and anatomist Korbinian Brodmann mapped the cerebral cortex and divided it into about 50 areas.
Katrin Amunts is developing a unique brain atlas that will gradually replace Brodmann’s map from 1909. Karl Zilles, and a large team of medical doctors, physicists, biologists, mathematicians and graduate students, Prof. Then the cellular architecture is statistically analyzed and digitally reconstructed in 3-D. The sections are analyzed using modern scanning microscopes and image analysis methods. The goal “is to develop a realistic, three-dimensional computer brain model based on structural, cytoarchitectonic, genetic, and molecular characteristics.” As part of this project, scientists at INM-1 are examining many thousands of histological brain sections. The human brain contains about 1,500 cm³ of brain tissue, and the terrain is quite something. Katrin Amunts and her team go on a unique research expedition: They create a three-dimensional atlas of the brainĪt first glance, the “route” is limited.
0 kommentar(er)
